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Revista Pan-Amazônica de Saúde
Print version ISSN 2176-6215On-line version ISSN 2176-6223
Abstract
JUSTINO, Maria Cleonice Aguiar; SOARES, Eliana Canen Pinto and AMORIM, Cláudio Sérgio Carvalho de. Dubin-Johnson syndrome: an important cause of obstructive jaundice in children. Rev Pan-Amaz Saude [online]. 2010, vol.1, n.3, pp.133-136. ISSN 2176-6215. http://dx.doi.org/10.5123/S2176-62232010000300018.
The Dubin-Johnson syndrome is clinically characterized by recurrent episodes of benign and familial obstructive jaundice. It is identified by the presence of melanic pigment in the hepatocytes. The authors report a case of Dubin-Johnson syndrome in a child with jaundice and hepatosplenomegaly, whose diagnosis was confirmed by the presence of dark brown pigment on microscopy of liver biopsy. They suggest the suspicion of this syndrome in cases of fluctuating obstructive jaundice in children.
Keywords : Cholestasis; Jaundice; Jaundice; Chronic Idiopathic.