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Boletim de Pneumologia Sanitária

Print version ISSN 0103-460X

Abstract

CAMPOS, Hisbello S. Mycobacterium tuberculosis resistente: de onde vem a resistência?. Bol. Pneumol. Sanit. [online]. 1999, vol.7, n.1, pp.51-64. ISSN 0103-460X.

The author discusses the resistant tuberculosis bacillii problem. He comments on the history of the Mycobacterium tuberculosis development and its inserction in the human ambient. He discusses the bacterial mechanisms used for developing resistance to the antibiotics, focusing on those used by the tuberculosis bacili and showing results of studies on the genetic modifications that leads to resistance. He presents some laboratorial instruments that can be used in the detection of resistance, commenting on its practical use. He ends by commenting on how a tuberculous patient can develop lesions colonized by resistant bacilii and the ways to avoid it.

Keywords : Resistant Mycobacterium tuberculosis; Multidrug resistant tuberculosis; Bacterial mechanisms of resistance.

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