Abstract

LIMA, Paula Ferraz de et al. Technical complaints and adverse drug events reported in a sentinel hospital in the state of São Paulo, 2009-2010. Epidemiol. Serv. Saúde [online]. 2013, vol.22, n.4, pp.679-686. ISSN 1679-4974.  http://dx.doi.org/10.5123/S1679-49742013000400014.

OBJECTIVE: to describe technical complaints and adverse drug events reported in a sentinel hospital in São Paulo state in 2009 and 2010. METHODS: This is a descriptive study. Information was obtained from the sentinel hospital Risk Management database. RESULTS: we found 199 reports related to drugs: 70.0% were technical complaints, 21.0% ineffective therapy and 9.0% adverse reaction to medication. The pharmacological groups with highest number of reports were: drugs that act on alimentary tract and metabolism (25.1%), the nervous system (25.1%) and anti-infective drugs for systemic use (22.1%). CONCLUSION: technical complaints and adverse drug events were frequent, despite recognized underreporting. The characterization of these events could inform the adoption of control measures and permanent educational actions in health services in order to prevent their occurrence.

Keywords : Pharmacovigilance; Medication Systems; Hospital; Adverse Drug Reaction Reporting Systems; Drug Toxicity; Epidemiology, Descriptive.

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