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Revista Pan-Amazônica de Saúde
versión impresa ISSN 2176-6215versión On-line ISSN 2176-6223
Resumen
PEREIRA, Washington Luiz Assunção et al. Jejunal injuries in captive marmosets affected by chronic wasting disease. Rev Pan-Amaz Saude [online]. 2021, vol.12, n.esp, e202100198. Epub 07-Jul-2021. ISSN 2176-6215. http://dx.doi.org/10.5123/s2176-6223202100198.
INTRODUCTION:
Wasting marmoset syndrome affects the Callitrichidae family reared in captivity, characterized by progressive muscle-weakening and wasting conditions. It has been one of the main causes of death in primates of this genus.
OBJECTIVE:
To evaluate the existence of histopathological and ultrastructural alterations in jejunal of marmosets that presented a clinical history of the progressive wasting disease in relation to healthy animals.
MATERIALS AND METHODS:
Jejunal biopsies of seven marmosets were performed: five of them, two specimens of Callithrix jacchus and three Callithrix penicillata, were affected by clinical signs of progressive weight loss and muscle weakness; and two healthy animals, one of each cited species, were used as control animals.
RESULTS:
Marmosets with a clinical history of progressive weight loss presented jejunal villus atrophy with a flattened surface; also the goblet cells were scarce and barely functional compared to the control animals.
CONCLUSION:
These changes can cause malabsorption of nutrients and promote the progressive weight loss of callitrichids.
Palabras clave : Callithrix; Intestinal Mucosa; Intestinal Diseases; Malabsorption Syndromes.