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Revista Pan-Amazônica de Saúde

versão On-line ISSN 2176-6223

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SILVA, Allan Kaio; SANTOS, Mirleide Cordeiro dos; MELLO, Wyller Alencar de  e  SOUSA, Rita Catarina Medeiros de. Ocurrence of Human Bocavirus associated with acute respiratory infections in children up to 2 years old in the City of Belém, Pará State, Brazil. Rev Pan-Amaz Saude [online]. 2010, vol.1, n.1, pp.87-92. ISSN 2176-6223.  http://dx.doi.org/10.5123/S2176-62232010000100013.

INTRODUCTION: Acute Respiratory Infections (ARI) are one of the main public health problems in the world. Most of these infections are associated with several pathogens, and viruses are the most prevalent agents. Recently, a new parvovirus named Human Bocavirus (HBoV) has been described. Investigations on the relationship between this new agent and cases of ARI in individuals are still scarce. Herein, we review a study of HBoV in a population segment in the Amazon. MATERIALS AND METHODS: In this study, samples of nasopharyngeal aspirates from patients with ARI treated in Health Care Units in Belém, Brazil, were analyzed. Identification of the virus was carried out by polymerase chain reaction using pairs of specific oligonucleotides, followed by phylogenetic analysis of the nucleotide sequences obtained. RESULTS: Of the 397 samples studied, three specimens were HBoV-positive, and one presented as a co-infection with the respiratory syncytial virus. DISCUSSION: The positivity rate obtained in this investigation was lower than that described in other studies; however, previous studies involved hospitalized patients, which constitute a different population group. The phylogenetic analyses revealed a significant similarity between the virus strains found and those previously described. CONCLUSION: This is the first report associating HBoV with ARI in the Amazon.

Palavras-chave : Respiratory Tract Infections; Bocavirus; Parvoviridae Infections.

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