Abstract

POLITI, Flávio Augusto Sanches; MOREIRA, Raquel Regina Duarte; SALGADO, Hérida Regina Nunes  and  PIETRO, Rosemeire Cristina Linhari Rodrigues. Preliminary tests on acute oral toxicity and intestinal motility with extract of pulverized bark of Endopleura uchi (Huber) Cuatrec. (Humiriaceae) in mice. Rev Pan-Amaz Saude [online]. 2010, vol.1, n.1, pp.187-189. ISSN 2176-6215.  http://dx.doi.org/10.5123/S2176-62232010000100026.

The aim of this work was to analyze the acute oral toxicity and the effects on intestinal motility of the extract obtained through decoction 20% (m/v) of Endopleura uchi, popularly known as "uxi-amarelo", a native plant from the Brazilian Amazon. The plant is used indiscriminately against several diseases: arthritis, cholesterol, diabetes, ulcers, myomas, and intestinal illnesses in general, among others. The present results show that there were no significant alterations in intestinal motility and that the extract does not present signs of toxicity, showing its safety for consumption purposes.

Keywords : Endopleura uchi; Gastrointestinal Motility; Acute Toxicity; Phytotherapy; Plant Extracts.

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