Abstract

NUNES, Heloisa Marceliano et al. Prevalence of infection with hepatitis A, B, C, D and E in a city of the West region of Pará State, Brazil. Rev Pan-Amaz Saude [online]. 2016, vol.7, n.1, pp.55-62. ISSN 2176-6215.  http://dx.doi.org/10.5123/s2176-62232016000100007.

In a survey on the prevalence of infection with hepatitis in the Municipality of Juruti, West region of Pará State, Brazil, conducted between February 2007 and April 2008, it was demonstrated the necessity to increase the seroprevalence studies based on communities. In order to meet this need, the study was expanded to define the prevalence of infections with virus of hepatitis A (HAV), B (HBV), C (HCV), D (HDV) and E (HEV), from February 2007 to November 2010, involving serum samples from individuals living in the center of the city and rural areas Café Torrado, Jauari, Nova Galiléia, Vila Muirapinima and Lago Jará, from the Municipality of Juruti, with estimated population of 52,755 inhabitants in 2014. These samples were submitted to analysis of serological markers of hepatitis A, B, C, D and E by enzyme immunoassay. In positive samples for HBV and HCV, researches were conducted for the detection of HBV-DNA and HCV-RNA. Among the 4,003 samples examined, the prevalence of total anti-HAV was 86.2%; 0.6% of HBsAg+; 8.3% anti-HBc+/anti-HBs+; 1.7% anti-HBc+ isolated; 33.4% anti-HBs+ isolated and HBV DNA+ in 62.5% of HBsAg+; 0.1% anti-HCV+. Among these, two cases have been confirmed as HCV by RT-PCR; among HBsAg+ cases there were not detected any carriers of HDV. The analysis of 463 samples collected in three rural communities in the city showed a prevalence of anti-HEV+ 1.9%. It was featured in laboratory-based, high prevalence of HAV infection and low prevalence of HBV, HCV, HDV and HEV in the examined population.

Keywords : Hepatitis A; Hepatitis B; Hepatitis C; Hepatitis D; Hepatitis E; Seroepidemiologic Studies.

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