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Revista Pan-Amazônica de Saúde
versão impressa ISSN 2176-6223versão On-line ISSN 2176-6223
Resumo
CUNHA, Maria Heliana Chaves Monteiro da et al. Risk factors in household contacts of leprosy patients using clinical, sociodemographic, and laboratorial variables. Rev Pan-Amaz Saude [online]. 2017, vol.8, n.2, pp.21-28. ISSN 2176-6223. http://dx.doi.org/10.5123/s2176-62232017000200003.
OBJECTIVE:
To identify risk factors in household contacts of leprosy patients, using clinical, sociodemographic, and laboratorial variables.
MATERIALS AND METHODS:
Cases series were investigated evaluating the household contacts of leprosy patients that were attended in a reference center in Pará State, Brazil, from 2012 to 2015. Dermatoneurological examinations, anti-PGL-I serology (ELISA, using cut-off point 0.2 and 0.13), and BCG vaccine control were performed, as well as clinical demographic data survey from the index case was conducted.
RESULTS:
There was higher predominance of the contacts that had been BCG vaccinated at least once (91.1%), higher seropositivity among contacts that present the disease multibacillary leprosy form, being more prevalent when the cut-off point was 0.13 (61.5%). The higest anti-PGL-I titrations were detected among the female group (51.1%), those that had elementary education (46.7%) and were among 15 to 40 years old (47.8%). The majority of individuals (91.4%) lived in houses with less than two rooms.
CONCLUSION:
It was concluded that low education level, age and living conditions may be risk factors for leprosy illness among household contacts of the multibacillary leprosy form; the younger age groups are more exposed to the bacillus contact; and that the anti-PGL-I serology is an important tool for tracking contacts of multibacillary leprosy forms.
Palavras-chave : Leprosy; Epidemiological Surveillance; Serology; Risk Factors.