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Revista Pan-Amazônica de Saúde

versión impresa ISSN 2176-6215versión On-line ISSN 2176-6223

Resumen

PARVAN, Lais Gonçalves et al. Allium cepa bioassay reveals genotoxicity of flumioxazin herbicide. Rev Pan-Amaz Saude [online]. 2020, vol.11, e202000544.  Epub 14-Sep-2020. ISSN 2176-6215.  http://dx.doi.org/10.5123/s2176-6223202000544.

OBJECTIVE:

To analyze the genotoxic potential of an herbicide with flumioxazin using the Allium cepa bioassay.

MATERIALS AND METHODS:

The herbicide was tested in two concentrations: 0.5 g/L (as indicated for use) and 1.0 g/L (twice the recommended concentration). Distilled water was used as a negative control and 1% sodium benzoate as a positive cytotoxicity control.

RESULTS:

Toxicity effects were evidenced in both herbicide concentrations. Cytotoxicity effects were observed in the herbicide with flumioxazin at a concentration of 0.5 g/L, which showed a microscopic pattern equal to that of the positive control. The effects of genotoxicity were observed at both concentrations (0.5 g/L and 1.0 g/L) which resulted in chromosomal aberrations in cells, showing that the herbicide directly interferes with the cell cycle of vegetal onion cells.

CONCLUSION:

The herbicide with flumioxazin showed toxicity and genotoxicity in the analyzed concentrations and effects of cytotoxicity only in the concentration recommended for use.

Palabras clave : Genotoxicity; Allium cepa; Herbicides; Mitotic Index.

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