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Revista Pan-Amazônica de Saúde

Print version ISSN 2176-6215On-line version ISSN 2176-6223

Abstract

MOTA JUNIOR, Max Chaves; GODINHO, Carmem Glória Palheta  and  CALDEIRA, Rossela Damasceno. Neglected tropical disease: a case report of chromoblastomycosis in the state of Pará, Brazil. Rev Pan-Amaz Saude [online]. 2025, vol.16, e202501797.  Epub Dec 04, 2025. ISSN 2176-6215.  http://dx.doi.org/10.5123/s2176-6223202501797.

INTRODUCTION:

Chromoblastomycosis (CBM) is a chronic, slowly progressing fungal infection with a polymorphic appearance that affects the cutaneous and subcutaneous tissues. It is caused by dematiaceous fungi found in soil, decomposing vegetation, plants, flowers, and wood.

OBJECTIVE:

To describe a case of CBM with chronic evolution and extensive lesion, emphasizing the importance of appropriate disease management.

CASE DESCRIPTION:

D.M.S., male, 56 years old, rural worker, resident in the state of Pará. He initially presented with a lesion on the right lower limb, which began as a small papule with inflammatory signs and progressed, within a few days, to a verrucous lesion. The patient was seen by several healthcare professionals and received various dermatological treatments, with no resolution of symptoms.

RESULTS:

A direct mycological examination was performed, with negative results for fungal structures. Subsequently, a vegetative lesion was excised and sent for biopsy. Histopathological examination revealed findings compatible with CBM. Treatment with itraconazole was initiated (two 100 mg capsules, taken orally twice daily for 12 months). At the end of treatment, the lesions had completely regressed, as had the associated symptoms, although residual macular lesions were still present.

CONCLUSION:

CBM is a neglected disease, and delays in diagnosis may lead to significant harm to affected individuals.

Keywords : Case Reports; Chromoblastomycosis; Neglected Diseases; Invasive Fungal Infections.

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