<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2176-6223</journal-id>
<journal-title><![CDATA[Revista Pan-Amazônica de Saúde]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Pan-Amaz Saude]]></abbrev-journal-title>
<issn>2176-6223</issn>
<publisher>
<publisher-name><![CDATA[Instituto Evandro Chagas. Secretaria de Vigilância em Saúde e Ambiente. Ministério da Saúde]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2176-62232017000300019</article-id>
<article-id pub-id-type="doi">10.5123/s2176-62232017000300003</article-id>
<title-group>
<article-title xml:lang="pt"><![CDATA[Prevalência da infecção pelo vírus da hepatite B em um município do interior do estado do Acre, Amazônia Ocidental, Brasil]]></article-title>
<article-title xml:lang="en"><![CDATA[Prevalence of hepatitis B virus infection in a municipality of Acre State, Western Amazonia, Brazil]]></article-title>
<article-title xml:lang="es"><![CDATA[Prevalencia de la infección por el virus de la hepatitis B en un municipio del interior del estado de Acre, Amazonía Occidental, Brasil]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Silva]]></surname>
<given-names><![CDATA[Rita do Socorro Uchôa da]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Morais]]></surname>
<given-names><![CDATA[Isadora Oliveira]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gonçalves]]></surname>
<given-names><![CDATA[Danielly Moreira]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Matos]]></surname>
<given-names><![CDATA[Irenilce Souza de]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rocha]]></surname>
<given-names><![CDATA[Francileide Ferreira da]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Torres]]></surname>
<given-names><![CDATA[Glivia Maria do Nascimento]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Costa]]></surname>
<given-names><![CDATA[Maria Lucimar Almeida da]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Silva]]></surname>
<given-names><![CDATA[Sueli Santiago da]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Silva]]></surname>
<given-names><![CDATA[Paula Alessandra Martins da]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Souza]]></surname>
<given-names><![CDATA[Renata]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Secretaria de Saúde do Estado do Acre  ]]></institution>
<addr-line><![CDATA[Rio Branco Acre]]></addr-line>
<country>Brasil</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidade Federal do Acre Centro de Ciências da Saúde e Desporto ]]></institution>
<addr-line><![CDATA[Rio Branco Acre]]></addr-line>
<country>Brazil</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>09</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>09</month>
<year>2017</year>
</pub-date>
<volume>8</volume>
<numero>3</numero>
<fpage>19</fpage>
<lpage>26</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.iec.gov.br/scielo.php?script=sci_arttext&amp;pid=S2176-62232017000300019&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iec.gov.br/scielo.php?script=sci_abstract&amp;pid=S2176-62232017000300019&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iec.gov.br/scielo.php?script=sci_pdf&amp;pid=S2176-62232017000300019&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="pt"><p><![CDATA[RESUMO  OBJETIVO: Estimar a prevalência do vírus da hepatite B (HBV) em indivíduos residentes no município de Porto Acre, estado do Acre, Amazônia Ocidental brasileira.  MATERIAIS E MÉTODOS: Estudo transversal, no qual foram incluídos moradores que compareceram por livre demanda às unidades básicas de saúde de Porto Acre, em 2012, aos quais se aplicou questionário padronizado e se coletou sangue venoso. Como triagem, usou-se teste rápido imunocromatográfico para hepatite B (HBsAg) e, diante do resultado reagente, foram realizados exames sorológicos (HBsAg e anti-HBc total). Os marcadores HBeAg, anti-HBe e anti-HD total foram utilizados exclusivamente nas amostras cujo HBsAg manteve-se reagente na sorologia.  RESULTADOS: Foram incluídas 646 pessoas (4,7% da população), sendo 57,6% do gênero feminino. Dezessete pessoas (2,6%) obtiveram testes rápidos reagentes para o HBsAg, dos quais em 82,3% (14/17) houve confirmação sorológica. O anti-HBc total foi reagente em 31,9% (206/646) dos indivíduos, dos quais 2,2% (14/646) com HBV atual e 29,7% (192/646) somente com evidência de infecção pregressa. Das 184 (28,5%) crianças e adolescentes incluídos na pesquisa, 9,2% (17/184) apresentaram contato prévio com o HBV. A ingestão abusiva de álcool apresentou correlação com reatividade ao HBsAg e ao anti-HBc total, enquanto faixa etária mais avançada, gênero masculino, cirurgias prévias e presença de tatuagens foram relacionados exclusivamente à maior reatividade ao anti-HBc total.  CONCLUSÃO: A prevalência da infecção pelo HBV em Porto Acre evidencia a gravidade da situação, visto que um terço da amostra do estudo já entrou em contato com o vírus, valor provavelmente subestimado, dado que 28,5% foi composta por crianças e adolescentes que, normalmente, são grupos menos acometidos.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  OBJECTIVE: To estimate the prevalence of hepatitis B virus (HBV) in individuals living in Porto Acre municipality, Acre State, Western Brazilian Amazon.  MATERIALS AND METHODS: Cross-sectional study carried out with residents of Porto Acre who had attended the basic health units in 2012 were invited to answer a standardized questionnaire and to donate venous blood. As screening, immunochromatographic rapid test (IRT) for hepatitis B (HBsAg) was used, and from whom that was reagent to the IRT, serological tests (HBsAg and total anti-HBc) were performed. The HBeAg, anti-HBe and total anti-HD markers were used exclusively in the samples whose HBsAg remained serologically reagent.  RESULTS: It was included 646 individuals (4.7% of the population), 57.6% of the female gender. Seventeen individuals (2.6%) were reagent to the IRT for HBsAg and of which in 82.3% (14/17) presented serological confirmation. Total anti-HBc was reactive in 31.9% (206/646) of the subjects, of which 2.2% (14/646) had current HBV and 29.7% (192/646) only evidence of previous infection. Of the 184 (28.5%) children and adolescents included in this study, 9.2% (17/184) had prior contact with HBV. The abusive alcohol intake is correlated to HBsAg and total anti-HBc reactivity, whereas older age, male gender, previous surgeries, and the presence of tattoos were related exclusively to total anti-HBc higher reactivity.  CONCLUSION: HBsAg seroprevalence was 2.2% and total anti-HBc approximately 32.0%. There was detection of total anti-HBc in 9.2% of the children and adolescents included in the study, evidencing early contact with HBV in this population.]]></p></abstract>
<abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  OBJETIVO: Estimar la prevalencia del virus de la hepatitis B (VHB) en individuos residentes en el municipio de Porto Acre, estado de Acre, Amazonía Occidental brasileña.  MATERIALES Y MÉTODOS: Estudio transversal, en el cual se incluyeron habitantes que comparecieron por libre demanda a las unidades básicas de salud de Porto Acre, en 2012, a los cuales se les aplicó un cuestionario estándar y se recolectó sangre venosa. Como selección, se usó prueba rápida inmunocromatográfica para hepatitis B (HBsAg) y, delante del resultado reactivo, se realizaron exámenes serológicos (HBsAg y anti-HBc total). Los marcadores HBeAg, anti-HBe y anti-HD total se utilizaron exclusivamente en las muestras cuyo HBsAg se mantuvo reactivo en la serología.  RESULTADOS: Fueron incluidas 646 personas (4,7% de la población), siendo 57,6% del género femenino. Diecisiete personas (2,6%) obtuvieron pruebas rápidas reactivas para HBsAg, de las cuales en 82,3% (14/17) hubo confirmación serológica. El anti-HBc total fue reactivo en 31,9% (206/646) de los individuos, entre los cuales 2,2% (14/646) con VHB actual y 29,7% (192/646) solamente con evidencia de infección anterior. De los 184 (28,5%) niños y adolescentes incluidos en el estudio, 9,2% (17/184) presentó contacto previo con VHB. La ingestión abusiva de alcohol presentó correlación con reactividad al HBsAg y al anti-HBc total, mientras que el grupo de edad más avanzado, género masculino, cirugías previas y presencia de tatuajes se relacionaron exclusivamente a una mayor reactividad al anti-HBc total.  CONCLUSIÓN: La prevalencia de la infección por VHB en Porto Acre evidencia la gravedad de la situación, visto que un tercio de la muestra del estudio ya entró en contacto con el virus, valor probablemente subestimado, dado que 28,5% se compuso de niños y adolescentes que, normalmente, son grupos menos acometidos.]]></p></abstract>
<kwd-group>
<kwd lng="pt"><![CDATA[Hepatite Viral Humana]]></kwd>
<kwd lng="pt"><![CDATA[Vírus da Hepatite B]]></kwd>
<kwd lng="pt"><![CDATA[HBsAg]]></kwd>
<kwd lng="pt"><![CDATA[Anti-HBc Total]]></kwd>
<kwd lng="en"><![CDATA[Human Viral Hepatitis]]></kwd>
<kwd lng="en"><![CDATA[Hepatitis B virus]]></kwd>
<kwd lng="en"><![CDATA[HBsAg]]></kwd>
<kwd lng="en"><![CDATA[Total Anti-HBc]]></kwd>
<kwd lng="es"><![CDATA[Hepatitis Viral Humana]]></kwd>
<kwd lng="es"><![CDATA[Virus de la Hepatitis B]]></kwd>
<kwd lng="es"><![CDATA[HBsAg]]></kwd>
<kwd lng="es"><![CDATA[Anti-HBc Total]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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