<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2176-6223</journal-id>
<journal-title><![CDATA[Revista Pan-Amazônica de Saúde]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Pan-Amaz Saude]]></abbrev-journal-title>
<issn>2176-6223</issn>
<publisher>
<publisher-name><![CDATA[Instituto Evandro Chagas. Secretaria de Vigilância em Saúde e Ambiente. Ministério da Saúde]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2176-62232025000110117</article-id>
<article-id pub-id-type="doi">10.5123/s2176-6223202501783</article-id>
<title-group>
<article-title xml:lang="pt"><![CDATA[Construção e validação de um instrumento digital para avaliar a percepção de pacientes quanto à adesão terapêutica da malária]]></article-title>
<article-title xml:lang="en"><![CDATA[Construction and validation of a digital instrument to assess patients' perception of therapeutic adherence in malaria]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Souza]]></surname>
<given-names><![CDATA[Karina Mayza Pereira de]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ferreira]]></surname>
<given-names><![CDATA[Victor Hugo Azevedo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Viana]]></surname>
<given-names><![CDATA[Danielle Socorro Rachid]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Chamma-Siqueira]]></surname>
<given-names><![CDATA[Nathália Nogueira]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Póvoa]]></surname>
<given-names><![CDATA[Marinete Marins]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Chaves]]></surname>
<given-names><![CDATA[Tânia do Socorro Souza]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Kahwage]]></surname>
<given-names><![CDATA[Cássia Maria Carneiro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Viana]]></surname>
<given-names><![CDATA[Giselle Maria Rachid]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto Evandro Chagas Programa de Pós-Graduação em Epidemiologia e Vigilância em Saúde ]]></institution>
<addr-line><![CDATA[Ananindeua Pará]]></addr-line>
<country>Brasil</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidade Federal do Pará Instituto de Ciências Exatas e Naturais ]]></institution>
<addr-line><![CDATA[Belém Pará]]></addr-line>
<country>Brazil</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Instituto Evandro Chagas Programa Colaborador Voluntário ]]></institution>
<addr-line><![CDATA[Ananindeua Pará]]></addr-line>
<country>Brasil</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Instituto Evandro Chagas Sessão de Parasitologia Laboratório de Malária]]></institution>
<addr-line><![CDATA[Ananindeua Pará]]></addr-line>
<country>Brasil</country>
</aff>
<aff id="Af5">
<institution><![CDATA[,Instituto Evandro Chagas Setor de Tecnologia da Informação e Comunicação ]]></institution>
<addr-line><![CDATA[Ananindeua Pará]]></addr-line>
<country>Brasil</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2025</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2025</year>
</pub-date>
<volume>16</volume>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.iec.gov.br/scielo.php?script=sci_arttext&amp;pid=S2176-62232025000110117&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iec.gov.br/scielo.php?script=sci_abstract&amp;pid=S2176-62232025000110117&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iec.gov.br/scielo.php?script=sci_pdf&amp;pid=S2176-62232025000110117&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="pt"><p><![CDATA[RESUMO  OBJETIVO:  Construir e validar o conteúdo de um instrumento digital com integração entre adesão terapêutica e ambiente-saúde, para identificar a percepção dos pacientes quanto à conduta relacionada à adesão ao tratamento da malária.  MÉTODOS:  Pesquisa metodológica estruturada em três etapas: revisão da literatura, construção do instrumento digital e validação de conteúdo por cinco juízes especialistas da área da saúde. Os dados foram analisados por estatística descritiva e submetidos à avaliação quantitativa pelo Índice de Validade de Conteúdo e pelo Coeficiente de Validade de Conteúdo.  RESULTADOS:  A revisão integrativa subsidiou a construção do instrumento digital. Os Índices de Validade de Conteúdo alcançados foram, no mínimo, 0,80 (80%), variando de 80% a 100%. O Coeficiente de Validade de Conteúdo apresentou índice de concordância geral de 0,86 (86%).  CONCLUSÃO:  O instrumento digital construído mostrou-se válido para futura aplicação e uso pelo público-alvo.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  OBJECTIVE:  To construct and validate the content of a digital instrument integrating therapeutic adherence and the health-environment interface to identify patients' perceptions regarding their conduct related to adherence to malaria treatment.  METHODS:  This methodological study was structured in three stages: literature review, development of the digital instrument, and content validation by five expert judges in the health field. Data were analyzed using descriptive statistics and quantitatively assessed through the Content Validity Index and the Content Validity Coefficient.  RESULTS:  The integrative review supported the development of the digital instrument. The Content Validity Index values were at least 0.80 (80%), ranging from 80% to 100%. The Content Validity Coefficient showed an overall agreement rate of 0.86 (86%).  CONCLUSION:  The digital instrument developed proved to be valid for future application and use by the target population.]]></p></abstract>
<kwd-group>
<kwd lng="pt"><![CDATA[Malária]]></kwd>
<kwd lng="pt"><![CDATA[Cooperação e Adesão ao Tratamento]]></kwd>
<kwd lng="pt"><![CDATA[Meio Ambiente e Saúde Pública]]></kwd>
<kwd lng="pt"><![CDATA[Saúde digital]]></kwd>
<kwd lng="en"><![CDATA[Malaria]]></kwd>
<kwd lng="en"><![CDATA[Treatment Adherence and Compliance]]></kwd>
<kwd lng="en"><![CDATA[Environment and Public Health]]></kwd>
<kwd lng="en"><![CDATA[Digital Health]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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