<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2176-6223</journal-id>
<journal-title><![CDATA[Revista Pan-Amazônica de Saúde]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Pan-Amaz Saude]]></abbrev-journal-title>
<issn>2176-6223</issn>
<publisher>
<publisher-name><![CDATA[Instituto Evandro Chagas. Secretaria de Vigilância em Saúde e Ambiente. Ministério da Saúde]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2176-62232021000100040</article-id>
<article-id pub-id-type="doi">10.5123/s2176-6223202100820</article-id>
<title-group>
<article-title xml:lang="pt"><![CDATA[Diagnóstico tardio de micose fungoide: um relato de caso]]></article-title>
<article-title xml:lang="en"><![CDATA[Late diagnosis of mycosis fungoides: a case report]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Lobato]]></surname>
<given-names><![CDATA[Brena Andrade de Lima]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
<xref ref-type="aff" rid="A a"/>
<xref ref-type="aff" rid="A4"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Brito]]></surname>
<given-names><![CDATA[João Augusto Gomes de Souza Monteiro de]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Carneiro]]></surname>
<given-names><![CDATA[Thiago Xavier]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Xavier]]></surname>
<given-names><![CDATA[Marília Brasil]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidade Federal do Pará Núcleo de Medicina Tropical Programa de Pós-Graduação em Doenças Tropicais]]></institution>
<addr-line><![CDATA[Belém Pará]]></addr-line>
<country>Brazil</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidade do Estado do Pará Centro de Ciências Biológicas e da Saúde Laboratório de Pesquisas em Dermatoses de Interesse Sanitário]]></institution>
<addr-line><![CDATA[Belém Pará]]></addr-line>
<country>Brazil</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital Ophir Loyola Divisão de Hematologia-Oncologia e Transplante de Células-Tronco ]]></institution>
<addr-line><![CDATA[Belém Pará]]></addr-line>
<country>Brazil</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Universidade Federal do Pará Núcleo de Medicina Tropical Laboratório de Pesquisas em Dermatologia Tropical e Doenças Endêmicas]]></institution>
<addr-line><![CDATA[Belém Pará]]></addr-line>
<country>Brazil</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2021</year>
</pub-date>
<volume>12</volume>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.iec.gov.br/scielo.php?script=sci_arttext&amp;pid=S2176-62232021000100040&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iec.gov.br/scielo.php?script=sci_abstract&amp;pid=S2176-62232021000100040&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iec.gov.br/scielo.php?script=sci_pdf&amp;pid=S2176-62232021000100040&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="pt"><p><![CDATA[RESUMO  INTRODUÇÃO:  Micose fungoide (MF) é um tipo de linfoma cutâneo de células T com incidência aproximada de 0,41/100.000 indivíduos anualmente. O presente relato ressalta os impactos do atraso diagnóstico na evolução da doença.  RELATO DO CASO:  Paciente do sexo feminino buscou assistência médica no serviço de dermatologia da Universidade do Estado do Pará (UEPA), em novembro de 2017, apresentando três placas eritemato-hipercrômicas infiltradas, duas no abdômen e uma descamativa no membro inferior esquerdo, e linfonodo palpável na região inguinal esquerda com crescimento progressivo que iniciou em 2011. A paciente relatou que havia sido submetida a vários exames e tratamentos, assistida por seis profissionais médicos de diferentes especialidades e realizado quatro exames histopatológicos. O caso foi investigado no serviço de dermatologia, tendo sido realizado estudo imunohistoquímico e concluído o diagnóstico de MF. A paciente iniciou tratamento com metotrexato 15 mg e ácido fólico 5 mg, em dose única semanal, e fototerapia com PUVA, tendo apresentado melhora significativa, porém, com extensa área de atrofia e infecções secundárias.  CONCLUSÃO:  O presente caso é um problema de saúde pública que reforça a necessidade de capacitação adequada de médicos para identificação e tratamento precoce de MF.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  INTRODUCTION: Mycosis fungoides (MF) is a cutaneous T-cell lymphoma with an incidence of approximately 0.41/100,000 individuals annually. This report highlights the impacts of delayed diagnosis on the evolution of the disease.  CASE REPORT: A female patient sought medical assistance at the dermatology service of the Universidade do Estado do Pará (UEPA), Brazil, on November 2017, due to three infiltrated erythematous-hyperchromic plaques, two on the abdomen and one scaly on the left lower limb, and a palpable lymph node in the left inguinal region with progressive growth which started in 2011. The patient reported that she had undergone several tests and treatments and was seen by six medical doctors of different specialties and underwent four histopathological exams. The patient's case was investigated in the dermatology service of UEPA; an immunohistochemical study was performed, concluding the diagnosis of MF. She was treated with methotrexate 15 mg and folic acid 5 mg in a single weekly dose and phototherapy with PUVA, showing significant improvement after treatment, but with an extensive area of atrophy and secondary infections.  CONCLUSION: The present case is a public health issue that reinforces the need for adequate medical training for early identification and treatment of MF.]]></p></abstract>
<kwd-group>
<kwd lng="pt"><![CDATA[Micose Fungoide]]></kwd>
<kwd lng="pt"><![CDATA[Perfil de Impacto da Doença]]></kwd>
<kwd lng="pt"><![CDATA[Diagnóstico Tardio]]></kwd>
<kwd lng="pt"><![CDATA[Acesso aos Serviços de Saúde.]]></kwd>
<kwd lng="en"><![CDATA[Mycosis Fungoides]]></kwd>
<kwd lng="en"><![CDATA[Health Impact Assessment]]></kwd>
<kwd lng="en"><![CDATA[Delayed Diagnosis]]></kwd>
<kwd lng="en"><![CDATA[Health Services Accessibility]]></kwd>
</kwd-group>
</article-meta>
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